Publications

Wilmington Endocrinology - Making the News

Shear wave elastography and parathyroid adenoma: A new tool for diagnosing parathyroid adenomas

author: Dr. Azizi et al. / published on July 18, 2016

Shear wave elastography and parathyroid adenoma: A new tool for diagnosing parathyroid adenomas

This study prospectively determines the shear wave elastography characteristics of parathyroid adenomas using virtual touch imaging quantification, a non-invasive ultrasound based shear wave elastography method. This prospective study examined 57 consecutive patients with biochemically proven primary hyperparathyroidism and solitary parathyroid adenoma identified by ultrasound and confirmed by at least one of the following: surgical resection, positive Technetium–99 m Sestamibi Scintigraphy (MIBI) scan, or fine needle aspiration biopsy with positive PTH washout (performed only in MIBI negative patients).

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Shear Wave Elastography and Cervical Lymph Nodes: Predicting Malignancy

author: Dr. Azizi et al. / published on March 17, 2016

Shear Wave Elastography and Cervical Lymph Nodes: Predicting Malignancy

This prospective study evaluates the accuracy of virtual touch imaging quantification (VTIQ), a non-invasive shear wave elastography method for measuring cervical lymph nodes (LN) stiffness in differentiating benign from malignant LN. The study evaluated 270 LN in 236 patients with both conventional B-mode ultrasound and VTIQ shear wave elastography before fine-needle aspiration biopsy (FNAB).

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Thyroid Nodules and Shear Wave Elastography: A New Tool in Thyroid Cancer Detection

author: Dr. Azizi et al. / published on August 13, 2015

Thyroid Nodules and Shear Wave Elastography: A New Tool in Thyroid Cancer Detection

This study determines the performance of virtual touch imaging quantification (VTIQ), a non-invasive shear wave elastography method for measuring thyroid nodule (TN) stiffness, in distinguishing benign from malignant TNs. This prospective study evaluates 707 TNs in 676 patients with fine-needle aspiration biopsy (FNAB).

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Association of Hashimoto’s thyroiditis with thyroid cancer: A Prospective Study

author: Dr. Azizi et al. / published on September 12, 2014

Association of Hashimoto’s thyroiditis with thyroid cancer: A Prospective Study

This prospective study investigates the relationship between Hashimoto’s thyroiditis (HT) and thyroid cancer (TC) in patients with thyroid nodules (TNs). We prospectively examined 2100 patients with 2753 TNs between January 5, 2010 and August 15, 2013. A total of 2023 patients with 2669 TNs met the inclusion criteria of TN >5 mm and age >18 years.

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Performance of Elastography for the Evaluation of Thyroid Nodules: A Prospective Study

author: Dr. Azizi et al. / published on November 8, 2012

Performance of Elastography for the Evaluation of Thyroid Nodules: A Prospective Study

In the ultrasound evaluation of masses, elastography measures stiffness, which may predict malignancy. We prospectively tested the hypothesis that TN stiffness, as measured by strain elastography (SE), is an independent predictor of thyroid cancer (TC) in unselected TNs.In 706 unselected patients with 912 TNs meeting the ATA criteria for a fine-needle aspiration biopsy (FNAB), we first performed conventional thyroid ultrasound and SE.

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Three-Dimensional US Images and Fine-Needle Aspiration Biopsy of a Thyroid Nodule

author: Dr. Azizi et al. / published on August 1, 2011

Three-Dimensional US Images and Fine-Needle Aspiration Biopsy of a Thyroid Nodule read full article

Autoimmune Thyroid Disease: A Risk Factor for Thyroid Cancer

author: Dr. Azizi et al. / published on March 1, 2011

Autoimmune Thyroid Disease: A Risk Factor for Thyroid Cancer

Objective: To examine the relationship between clinical markers of autoimmune thyroid disease and the risk of thyroid cancer in patients with thyroid nodules.  A retrospective cohort analysis was performed in a single clinical practice. In 2,500 consecutive patients, fine-needle aspiration biopsy (FNAB) was performed on all 3,658 ultrasonography-positive thyroid nodules that were ≥1.0 cm in diameter or ≥0.5 cm in diameter with ultrasound features suspicious for thyroid cancer. Serum concentrations of thyroglobulin antibodies (TgAb), thyroid peroxidase antibodies, and thyroid-stimulating hormone were measured before FNAB. Diagnosis of thyroid cancer was based on pathologic analysis of thyroidectomy tissue. Associations of thyroid cancer with the independent variables were determined by multivariate logistic regression analysis and reported as the adjusted odds ratio (OR) with the 95% confidence interval (CI).

 

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Effect of micronized progesterone on bone turnover in postmenopausal women on estrogen replacement

author: Dr. Azizi et al. / published on May 10, 2003

Effect of micronized progesterone on bone turnover in postmenopausal women on estrogen replacement

PURPOSE: To determine whether daily oral micronized progesterone affects bone turnover, as estimated by serum and urine biochemical markers, in postmenopausal women on long-term estrogen replacement therapy (ERT).We recruited 14 women aged 65 or older to participate in a 9-week trial with micronized progesterone. Each woman had undergone a hysterectomy and was on unopposed ERT at time of study entry. Women received micronized progesterone 100 mg twice daily in the first week and then received 200 mg twice daily in weeks 2-9. We measured markers of bone turnover in serum and urine collected at baseline and at 3 weeks, 6 weeks, and 9 weeks on treatment.

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An Endocrine Practice Case Report – Visual vignette: Grave’s disease

author: Dr. Azizi et al. / published on November 10, 2000

An Endocrine Practice Case Report – Visual vignette: Grave’s disease read full article